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Clinical studies show efficacy at concentrations as low as 0.01 nM, with optimal results at 1100 nM (Maquart et al., 2015)

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What these differences imply for research For a laboratory working on these compounds, the distinctions in pathways have concrete consequences for binding assays and in vitro models

1 Two caveats matter: the peptide tested was AHK-Cu (copper tripeptide-3), a close cousin of GHK-Cu but not the same molecule, and the work was in cultured follicles and cells, not on human scalps

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