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A patch test is recommended before broader use

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Symptoms can vary from person to person, but may include: Nausea/vomiting Bloating or digestive issues Diarrhea Constipation Abdominal pain or gas Headache or migraine Fatigue Runny or stuffy nose Itching Rash/hives Shortness of breath Fast or irregular heart rate Flushing Low blood pressure Swelling of lips, tongue, or throat Irregular menstrual cycle In more severe cases, patients may experience cramping, high blood pressure, anxiety or dizziness, and trouble regulating body temperature

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Status spongiosus of CNS and hepatic changes induced by cuprizone (biscyclohexanone oxalyldihydrazone)

The research was supported by the National Institutes of Health