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Rodent models have contributed significantly to our understanding of synaptic physiology, but growing evidence points to distinctive features of human neurons that are not fully captured in rodents 5 , making direct investigation in human cells essential for studying synaptic pathologies linked to cognitive decline

6 With regard to metabolism , individuals inherit different metabolic predispositions

Whereas low rhGH-doses did not result in significant changes in GFR or glomerular sclerosis index compared to controls, medium and high-dose rhGH-treatment resulted in a significantly lower creatinine clearance and glomerularsclerosis index

Diabetes 54 (9), 27342743

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