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Thyroid hormone stimulates protein synthesis in the cardiomyocyte by activating the Akt-mTOR and p70S6K pathways

Exogenous supplementation of LF could also improve energy metabolism (26, 27)

By blocking NNMT, 5-Amino-1MQ: increases NAD+ levels, enhances cellular energy and mitochondrial function, promotes lipolysis (fat breakdown), and activates SIRT1 (longevity gene) pathways

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Results and discussion Preparation and characterization of Cel-BR and HA-RM-Cel-BR Based on the toxicity of Free Cel and the ROS scavenging evaluation of BR (Figures S1-S3), we investigated the self-assembly of nanomedicine Cel-BR using Cel and BR at mass ratios of 1:10, 1:15, and 1:20