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doi: 10.3389/fimmu.2026.1793440 Received 22 January 2026 Revised 25 February 2026 Accepted 06 March 2026 Published 23 March 2026 Volume 17 - 2026 Edited by Baocun Zhang, Aarhus University, Denmark Reviewed by Yibo Ma, Second Affiliated Hospital of Dalian Medical University, China Daniela Poenaru, Carol Davila University of Medicine and Pharmacy, Romania Updates Copyright 2026 Chen, Gao, Luo, Wang, Niken, Xu, Ding and Guo

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Recent guidelines suggest that patients with uncomplicated acute diverticulitis be managed without antibiotics as outcomes are similar to those for patients treated with antibiotics in this situation