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In the ischemia-reperfusion (I/R)-AKI model, the E3 ligase Trim21 is highly expressed, which modulates AKI by ubiquitinating degradation of glutathione peroxidase 4 (GPX4)

This disease is popularly known as "dislodged crystals" and affects 10 percent of the population

Spira A, Wertheim MS, Kim EJ, Tan B, Lenz HJ, Nikolinakos P, Rich PL, Jehl G, Machl A, Ito R, Gulley JL, Kopetz S

Patients should eat slowly, recognize satiety cues earlier, and stop eating when comfortably satisfied rather than full

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