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Because IGF-1 LR3 has no FDA pathway and is sold only as a "research chemical," there is no mandatory COA standard, no USP monograph, and no enforcement of purity claims

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31 A report on a placebo-controlled clinical trial indicated 9 of 12 rosacea patients treated with a 5% vitamin C cream had measurable improvement in facial redness

Using tretinoin: apply a pea-sized amount to clean, dry skin at night (dampness increases penetration and irritation)

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