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Plasmids and site-directed mutagenesis For the RNA interference-mediated knockdown of KEAP1, we used the lentiviral plasmid pLKO.1 from the TRC shRNA library (Sigma-Aldrich, Milan, Italy) expressing specific shRNA for 3UTR of human KEAP1 (#TRCN0000155340) or GFP as negative control [65]

ARE, Antioxidant Response Elements

doi: 10.1097/MAO.0000000000000466

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Y.TyurinV

10.13863/j.issn1001-4454.2002.05.023 90 XuH.LiL.WangS.WangZ.QuL.WangC.et al (2023)