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Key factors determining antioxidant efficacy include metal chelation, free radical scavenging selectivity, bioavailability, gene expression regulation, synergy with other antioxidants, and capacity to repair oxidative damage

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Because all congenic and allogeneic animals maintained measurable chimerism levels 2 weeks after IUHCT, it seemed that engraftment failure was a postnatal occurrence, supporting the presence of a previously unrecognized adaptive immune barrier

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