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Central nervous system applications are an active growth area, with documented effects on dopamine and serotonin pathway markers, traumatic brain injury models, and spinal cord research preparations

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Interestingly, in contrast to these findings, angiogenesis is hypothesized to be present in brains of PD patients, induced by stressors like hypoxia or inflammation [177, 178]

TSLP is abundantly expressed in keratinocytes of AD lesions and promotes Th2-type inflammation while directly activating transient receptor potential ankyrin 1 (TRPA1) channels on sensory neurons, enhancing pruritus (Wilson et al., 2013

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