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In contrast to and m 1 , lipofection of bone marrow stem cells with 5moU-modified mRNA did not induce IFN- or IL-6 secretion, nor did it trigger caspase activation [282]

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In Q1 2025, 339 Type II filings were recorded.Across all DMF types (II, III, IV, and V), 479 DMFs were filed in Q3 2025, compared to 394 in Q3 2024, representing a 21.57 percent increase