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Among the shared proteins between EVs and ExerVs, the top significantly upregulated proteins included integrin beta-1 (ITB1), calponin-2 (CNN2), fibronectin (FINC), myosin light polypeptide 6 (MYL6), alpha-enolase (ENOA), myosin regulatory light chain 12A (ML12A), and myosin regulatory light chain 12B (ML12B), thrombospondin-1 (TSP1), fibrinogen gamma chain (FIBG), integrin alpha-6 (ITA6), cofilin-1 (COF1), ras-related protein Rap-1b (RAP1B), vasodilator-stimulated phosphoprotein (VASP), (Fig

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Every treatment begins with a consultation, lab review, and individualized dosing strategy

Do not freeze the vials or expose them to excessive heat

A specific gut microbiota dysbiosis of type 2 diabetic mice induces GLP-1 resistance through an enteric NO-dependent and gut-brain axis mechanism

The nanocarriers were synthesized as shown in Fig