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Kastin AJ et al

NAC also theoretically increases bleeding risk with anticoagulants and antiplatelet drugs, and may lower blood pressure further with blood pressure medications

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Altogether, we suggest further comprehensive evaluation of TQ in preclinical and clinical levels to delineate its implied utility as a novel complementary adjuvant therapy for cancer treatment

H 2 O 2 produced during the oxidative folding of endoplasmic reticulum proteins has been found to regulate the signal transduction process of nuclear factor E2-related factor 2 (Nrf2), which in turn regulates the expression of downstream glutathione peroxidase 8 (GPX8), which in turn can participate in ER calcium regulation through endoplasmic reticulum calcium ATPase (SERCA) (Figure 7)