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J Biol Chem 2000
KPV: 500 to 1,500 mcg per day orally, or 200 to 500 mcg per day subcutaneously
Indianapolis has a meaningful concentration of functional-medicine-trained physicians, and several local peptide clinics in our directory publish menus that extend beyond GLP-1s into longevity peptides (Epitalon, Selank, Semax) and tissue-recovery compounds (BPC-157, TB-500)
10.1152/japplphysiol.00704.2003 2 BaileyD
The intranasal GHK-Cu treatment was found to delay cognitive impairment, reduce amyloid plaques, and lower inflammation levels in the frontal cortex and hippocampus .37 Randomized controlled trials in human patients are needed to confirm the benefit of GHK-Cu for cognitive decline and Alzheimers disease as well as to evaluate safe and effective human dosing (the human dose equivalent of 15mg/kg in mice would be ~1.2mg/kg, though data on this or any other dosing nasally in humans is not currently available), but preliminary animal trials are promising
