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In acute BI, erianin exerts a protective effect through a dual mechanism: In cerebral ischemia-reperfusion injury, erianin inhibits microglia-mediated neuroinflammation by regulating the PI3K/AKT and NF-B pathways (111)

The gut and immune system also depend on microbes

(2019) Cystathione beta synthase deficiency and brain edema associated with methionine excess under betaine supplementation: Four new cases and a review of the evidence, JIMD reports, Vol

Mol Cell Biochem 282:7582

A systematic review and network meta-analysis was performed to assess the effects of these supplements on TPOAb, TgAb, and TSH, based on recently published randomised controlled trials

Code availability All atomic models and code associated with molecular dynamics simulations can be found at References Porter, K