The body's own enzyme diamine oxidase (DAO), which is mainly produced by the cells of the intestinal mucosa but is also found in the blood, plays a key role in the breakdown and the associated disruption
If administered parentally, or if administered concurrently in the presence of an MAO inhibitor, elevated levels of plasma tyramine are taken up by presynaptic neuronal NET transporters which induces the release of norepinephrine
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That said, Agm treatment does more consistently protect such memory traces from disruption by subsequent insults, suggesting a role for Agm co-transmission in maintaining these types of learning (Moosavi et al., 2014
