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Front Neurosci 12:214 Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Radmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Forster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, O'Donnell VB, Kagan VE, Schick JA, Conrad M (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Protecting against lipid peroxidation is of utmost importance, since it is a self-propagating chain reaction, and the initial oxidation of only a few lipid molecules can result in significant tissue damage

Mol Biol 38(2):244249 Funding Open access funding provided by the Scientific and Technological Research Council of Trkiye (TBTAK)

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Russ J Bioorg Chem 34, 415420

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