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Scian M, Le Trong I, Mazari AMA, Mannervik B, Atkins WM, Stenkamp RE

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Pharmacokinetics, pharmacodynamics, and pharmacogenomics of immunosuppressants in allogeneic hematopoietic cell transplantation: Part II

45 Likewise, sleep deprivation in both humans and animals lowers total glutathione and impairs antioxidant defenses in various tissues

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The use of prazosin, an 1-adrenergic receptor blocker, showed that the ability of GLP-1RAs to reduce TNF- in plasma was disrupted, signifying the vital role of 1-adrenergic receptors in the anti-inflammatory action of GLP-1RAs