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NAD+ supplementation (via NAD+, NMN, or NR) addresses the NAD+ deficit by adding more precursor substrate from outside the cell
SAM does the following: Breaks down estrogens Carnitine synthesis (the fat carrier molecule of the body) Choline synthesis Creatine synthesis Epinephrine synthesis Melatonin synthesis (aids in sleep, a powerful antioxidant) Nucleic acid synthesis- a component of DNA Breakdown of histamine Glutathione synthesis (the major detox antioxidant of the body) Maintains cartilage health Inositol: A B vitamin and a primary component of cell membranes
Two practical consequences fall out of this mechanism, and both explain the shape of the protocol below
It doesn't work like caffeine or a stimulant
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