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Repeated measures REML Mixed Models were used to reflect the design and properly compare preparation condition within each subject before amalgamating these comparisons across subjects

Semaglutide (Wegovy and Ozempic) is FDA-approved for managing blood sugar levels in patients with type 2 diabetes mellitus and promoting weight loss in obese and overweight patients with at least one weight-related health condition, when used along with lifestyle changes such as a low-calorie diet and increased physical activity

2.1.6 Mitochondrial function assay The mitochondrial suspension was obtained from heart tissue using the mitochondrial extraction kit (G006-1-1, Jiancheng, Nanjing, China)

Study 3: IV safety (2025)