NGR-based strategies for targeting delivery of chemotherapeutics to tumor vasculature
Most formulations are designed for easy use, often as capsules, powders, or subcutaneous injections (consult your healthcare provider for guidance here)
Mechanistically, the peptide has been studied as a pro-angiogenic agent that appears to work through the VEGFR2 receptor and the endothelial nitric-oxide synthase (eNOS)nitric-oxide pathway, and as a stimulator of fibroblast outgrowth and migration through the FAKpaxillin signaling pathway
Products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S
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No blinded assessment