Asparagine may also coordinate the protein and nucleotide synthesis through the regulation of mTORC1 activity [65]
At doses of 150250 mg/kg, DHM improved neurological function, reduced brain edema, and infarct size in a dose-dependent manner
Light, oxygen, and moisture can impact small-molecule stability
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We chose P90 as the time of investigation, because this is a symptomatic stage with profound CSMN loss, and it coincides to the disease stage, when patients show symptoms and TDP-43 pathology begins to occur
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