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For the emulsion-evaporation method, PLGA polymer was dissolved in a dispersion of DDA- GSH-AuNCs in dichloromethane, which was then emulsified into aqueous external phase

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PC3 cell line: 100 g

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Loss of intracellular GSH is likely multifactorial and includes generation of high levels of hydroperoxy-phospholipids (which directly or indirectly oxidize GSH and limit GSSG recycling by reductases) as well as active export of GSSG generated by high GPX4 activity (7, 8, 21)