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Nutrients 12(6):1562

doi: 10.1016/j.virol.2010.11.005

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In both the B16F10 melanoma and E.G7-OVA lymphoma model, TDLN-targeting nanoparticle (NP)-conjugate vaccines induced substantially stronger local and systemic cytotoxic CD8+ T-cell responses when compared to non-TDLN-targeting vaccination, leading to enhanced tumor regression and host survival (237)