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Rather surprisingly, this suggests that the benefits of reduced mTORC1 signaling, and increased autophagy may be mediated primarily by an A-independent mechanism and moreover, previous studies have demonstrated that mTORC1 inhibition leads to the suppression of tauopathy 65,66

Laboratory handling note: Lyophilized compounds are commonly reconstituted using sterile research diluents such as bacteriostatic water (BAC).

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These generated 33 identified benefits to the AF (see Table 4-1)

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