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Design of high-affinity stapled peptides to target the repressor activator protein 1 (RAP1)/telomeric repeat-binding factor 2 (TRF2) proteinprotein interaction in the shelterin complex

As with all research compounds, investigators should implement appropriate laboratory safety protocols and follow institutional guidelines for handling investigational chemical compounds in controlled research environments

At the same time, they showed that localization of L-K6 through clathrin-independent micropinocytosis, without disturbing the cell surface in the cells, causes nuclear damage and cell death, without significant disruption of the cytoskeleton and mitochondrial dysfunction [77]

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pH 7.4) were prepared for photoinactivation assays