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Published online March 6, 2023 DOI: 9,910 View 219 Download 3 Web of Science 3 Crossref Abstract PDFSupplementary MaterialPubReader ePub Background Leptin is a 16-kDa fat-derived hormone with a primary role in controlling adipose tissue levels

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Interestingly, several fragment hits originating from our second XChem screen possess alternative groups to the sulfonic acid that interact with R131 and R102, which opens up opportunities to link and merge hit matter found across the TIN2 leucine and phenylalanine binding pockets