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In general, SSTR expression is reduced in cancer because of methylation of the promotor region

doi: 10.1002/ddr.20250

Also, it acts as a cofactor in enzyme complexes (139)

Redox control of apoptosis: An update [Research Support, Non-U.S

(2003) Bone n=18 Long-term study showing ipamorelin enhanced bone formation markers and improved bone mineral density

B12 is stored quite well by the liver, so sometimes we dont see low levels on bloodwork even in someone who might be experiencing low intracellular levels of B12