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"Structural basis for DNA recognition by FoxO1 and its regulation by posttranslational modification"

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By inhibiting these metabolic pathways, metformin further increases the apoptosis rate of tumor cells (67)

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Es agiert dabei als Vermittler, der diese schdlichen Elemente in wasserlsliche Formen berfhrt und somit ihre Ausscheidung ber die Nieren ermglicht

doi: 10.1080/10629360601053893