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Generation of PE rat models with different p53 expression levels Female and male SpragueDawley rats aged 68 weeks and weighing 180 ~ 200 g without a mating history were randomized into four groups of eight rats in each group as follows: (1) p53-overexpressing (p53 +/+) group: before pregnancy, 40 mg/kg of the p53 inducer Nutlin-3 was intraperitoneally injected every 2 days for 14 consecutive days, and 125 mg/kg/day L-NAME was intraperitoneally injected on the 7 th day of pregnancy for 7 consecutive days

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Xu H., Zhong L., Deng J., Peng J., Dan H., Zeng X., Li T., Chen Q

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What are the signs of serious adverse reactions to HCG