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[DOI] [PubMed] [Google Scholar] 24.Gannon M.C., Nuttall J.A., Nuttall F.Q

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In a clinical study involving patients with refractory SLEdefined as those with persistent disease activity despite high-dose glucocorticoids and/or cytotoxic drugsthe combination of Low-dose IL-2 (100 WIU, 35 days/month) and rapamycin(0.5 mg every other day) demonstrated synergistic effects (272)

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