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In their study of passive exposure to exhaled e-cigarette aerosol in a simulated caf, Schober et al 39 found that concentrations of fine particles in the air increased from a median of 400 particles per 1 cm 3 with people simply sitting in the room for 2 hours to medians of 49 000 to 88 000 particles per 1 cm 3 (depending on the e-cigarette fluid used) after 2 hours of e-cigarette use in the same room Both the e-liquid and the Poly-fil fibers that are used to absorb the e-liquid for heating and conversion to an aerosol come into contact with heating elements that contain heavy metals (tin, nickel, copper, lead, chromium)