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In summary: SAG provides direct, synthesis-independent intracellular GSH delivery, making it particularly suited for research models where the GSH synthesis pathway may be compromised or where researchers require rapid, direct intracellular GSH loading

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Based on a comprehensive analysis of the literature, we propose that BACH1 is a typical context-dependent transcription factor, and its function is strongly regulated by the intracellular redox state: ROS levels and heme metabolism significantly influence the expression and activity of BACH1

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