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We also compared these two groups with a cohort of healthy controls (HCs, unexposed to SARS-CoV-2), and with patients suffering from a severe form of acute COVID-19 (A) who were admitted to the Intensive Care Unit (ICU)

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These preliminary findings contribute to a deeper understanding of the biological processes underlying DOR and may offer a theoretical basis for the future development of targeted therapeutic strategies

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The median fluorescence intensity (MFI) of Calcein, the fluorescent product in the Calcein-AM assay of live cells was recorded in the FITC channel of a FACS Canto II flow cytometer (BD Biosciences), and analyzed with the FlowJo software (FlowJo, LLC)