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REDEFINE 2 included 1,206 participants with overweight or obesity and type 2 diabetes

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The important topic is how social stress induces temporary changes in the epigenetic network and whether gene expression might contribute to long-term socialbehavioural adaptations

Proteins were further digested with trypsin at 1:50 overnight at 37 C under agitation at 78 g to produce peptides for mass spectrometry (MS) analysis