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Endocrinology 148 , 45364544 (2007)

While not primarily a fat loss compound, these effects support body recomposition when combined with appropriate training and nutrition

The skin is the first organ to show the effects, though it permeates the entire body

Fulton, B

Common upstream drivers in Hashimotos Gluten and cross-reactive foods in susceptible individuals Intestinal permeability (leaky gut) and mucosal barrier injury Dysbiosis (microbiome imbalance) and chronic GI inflammation Micronutrient deficits that impair antioxidant defense and immune regulation High stress physiology with poor sleep and autonomic dysregulation Infections that drive immune activation in genetically susceptible hosts Environmental toxins that increase inflammatory burden Gut health is central because a large portion of immune regulation occurs at the gut-immune interface