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Clinical signs are indistinct and include lethargy, depression, ataxia, anorexia and intermittent vomiting, and in severe cases, can induce neurological disease and blindness in cats

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Moreover, NTAPP did not induce significant apoptosis which was verified by flow cytometry and quantitative RT-PCR (qRT-PCR) for apoptosis-related genes (Supplementary Figure 1b, 1c)