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Alpha-Lipoic Acid/Safety - Professional Handout

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It has been shown to influence the expression of genes involved in angiogenesis (e.g., egr-1), stabilize endothelial integrity, and facilitate the recruitment of fibroblasts to injury sites 4

In the 1970s, Prescott and coworkers in the UK used an IV protocol [15], while Rumack and coworkers in the US developed a 72-hour oral treatment protocol because the US Food and Drug Administration did not approve the use of the mucolytic drug by the IV route [60]

What are the contraindications to B12 (cobalamin) injections in patients with various medical conditions, including allergies, Leber's optic neuropathy, pregnancy, breastfeeding, kidney disease, liver disease, and those taking medications like chloramphenicol (antibiotic)?

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