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[6] First-line pharmacological treatments include phosphodiesterase type 5 (PDE5) inhibitors, which are licensed, well-studied medications: Sildenafil (Viagra): Typically effective within 30-60 minutes, lasting 4-6 hours [7] Tadalafil (Cialis): Longer duration of action (up to 36 hours), also available as daily low-dose formulation [8] Vardenafil (Levitra): Similar efficacy to sildenafil with slightly different pharmacokinetics Avanafil (Spedra): Take approximately 30 minutes before sexual activity

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Its also possible negative outcomes could be underreported

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Physicians should consider timely referral to higher levels of care and specialists whenever needed

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Low blood sugar (hypoglycemia): Symptoms may include headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery

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Real-world data shows how often people restart, but not whether a second course reaches the same low point

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