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The ability to recapitulate individual human pathophysiology in a controlled system will not only advance personalized therapeutic strategies but also enable trial-on-chip approaches that anticipate clinical responses and reduce exposure to ineffective treatments

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Catalase activity increases for hydrogen peroxide breakdown, and total glutathione levels rise, creating stronger hydroxyl radical quenching capacity than glutathione alone

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Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gtzsche PC, Ioannidis JPA, et al