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Moreover, intersections between upregulated DEGs in the control group and downregulated DEGs in the treatment groups, as well as between downregulated DEGs in the control group and upregulated DEGs in the treatment groups, also demonstrated that the combination group had a greater overlap with the control group than either single-drug group did (Additional file 2: Figure S5)

Hanukoglu I (2017) Conservation of the enzymecoenzyme interfaces in FAD and NADP binding adrenodoxin reductasea ubiquitous enzyme

Park K, Shin JW, Oh JK, Ryu KS, Kim SW, Paick JS

When the intestinal barrier is damaged, resulting in congenital immune dysregulation, the adaptive immune system becomes crucial

0.96%, respectively) (Table 1)

Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice