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How a B12 deficiency causes fatigue Your cells need B12 for proper function, and without the necessary amount, your red blood cell production decreases, which makes delivering oxygen to your cells more difficult

This outcome is more common with severe structural issues, very long-standing chronic pain, or conditions better addressed by other interventions

Lysenko et al

Clinical trials commonly start with 1 mg weekly and gradually increase the dose to higher levels such as 4 mg, 8 mg, or even 12 mg depending on the study protocol

This approach treats GHK-CU as a maintenance supplement rather than an intensive intervention

Discuss with a healthcare provider to determine the best timing for you