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Lentiviral CRISPR epigenome editing of inflammatory receptors as a gene therapy strategy for disc degeneration
doi: 10.3389/fphar.2025.1656316 Received 29 June 2025 Accepted 12 August 2025 Published 22 August 2025 Volume 16 - 2025 Edited by Barbara Ruaro, University of Trieste, Italy Reviewed by Mohammad Irshad Reza, North Dakota State University, United States Burak Okyar, Ministry of Health, Trkiye Jacopo Simonetti, Universit cattolica del Sacro Cuore di Roma, Italy Updates Copyright 2025 Zhang, Zhang, Hu and Zhang
Research shows that B7 33 binds to receptors involved in tissue repair and may reduce fibrosis and scarring in some experimental models
The ability to obtain the compound through legitimate medical channels also provides quality assurance benefits, as regulated pharmacies must meet standards for purity and potency that unregulated suppliers do not
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