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Increased aqueous solubility facilitates subsequent transport across cellular and canalicular membranes and promotes elimination of the conjugated metabolites via urine or bile

Science 354 , 572577 (2016)

Glycine, cysteine, and glutamate leave the blood by transport into liver cells (depending on their concentrations) and they are also formed in the blood by the breakdown of GSH and GSSG into their component amino acids [37, 38]

Germande O, Ducret T, Quignard JF, Deweirdt J, Freund-Michel V, Errera MH, Cardouat G, Vacher P, Muller B, Berger P, Guibert C, Baudrimont M, Baudrimont I (2022) NiONP-induced oxidative stress and mitochondrial impairment in an in vitro pulmonary vascular cell model mimicking endothelial dysfunction