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A comprehensive review would synthesize findings from various studies, including Systematic reviews, umbrella reviews, randomized controlled trials and observational studies, to provide clearer guidance for clinicians and patients alike (13, 14)

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(PubMed) Yamanaka G, Suzuki S, Takeshita M, et al

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This interaction is likely to be especially important in HTG-AP, in which overwhelming delivery of triglyceride-derived non-esterified fatty acids (NEFAs) creates a lipotoxic environment that exceeds the oxidative capacity of a single organelle system