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OBM Geriatrics 2018;2(3):009;doi:10.21926/obm.geriatr.1803009

Devarbhavi H, Raj S, Aradya V, Rangegowda V, Veeranna G, Singh R, Reddy V, Patil M

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It has been studied extensively for its potential influence on molecular signaling, structural remodeling, and angiogenic processes

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Most of these findings are absent in the younger euthymic bipolar population, pointing to the progressive nature of bipolar disorder, whereby cortico-limbic dysfunction becomes consolidated over time into a trait-like pattern of activity (146)