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Uses the current dose and calendar frequency

The titration protocol exists for safety reasons that are independent of any co-administered compound

By activating these receptors in the brains satiety centers (like the area postrema), it promotes feelings of fullness, reduces food intake, and helps stabilize post-meal blood sugar spikes, making it a promising candidate for weight management, particularly in combination with the GLP-1 receptor agonist semaglutide (marketed as CagriSema)

Renal function: mild eGFR changes observed in some patients

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