Wound healing assay showed that ferroptosis counteracted RhoA knockdown-induced decrease in migration in IL-1-treated ECs (Fig
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Moreover, we identified four species, ( Xestospongia bergquistia , Nematostella vectensis , Ciona intestinalis , and Branchiostoma floridae ) that do not have any peroxisomal CAT but instead encode a cytoplasmic CAT (Fig
GSH has long been implicated as a major antioxidant and redox regulator that functions to mitigate and alleviate this oxidative damage ( However, the preceding sections of this paper establish that GSH is not merely a passive antioxidant, but an immune regulator and modulator with actions dependent upon the pathophysiologic context (Tieu et al., 2023