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doi: 10.1136/pgmj.2009.087452 2 BarkhofKoeller

This study elucidated the in vitro neuroprotective potential of unripe durian fruit pulp extract (UDE) against H 2 O 2 -induced neurotoxicity in SH-SY5Y cells and neuroinflammation in lipopolysaccharide (LPS)-stimulated BV-2 cells

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Multifunctional low-temperature photothermal nanodrug with in vivo clearance, ROS-scavenging and anti-inflammatory abilities

However, despite a sound mechanistic rationale, no NMDA receptor antagonist has yet received regulatory approval for tinnitus treatment, reflecting the substantial challenges remaining in this field (Che et al., 2025)