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Neurodegenerative diseases Mitochondrial dysfunction has been associated with the onset and/or development of neurodegenerative diseases (Arun et al., 1995)

A 2021 review in Nature Reviews Molecular Cell Biology describes a gradual drop in tissue and cellular NAD+ across aging in rodents and humans, and links that fall to metabolic disease, cognitive decline, and sarcopenia [1]

DAutraux B, Toledano MB

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Extensive studies suggest that carotenoids may inhibit neurodegenerative diseases through a variety of molecular mechanisms [68,69]

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